For which medication must dispensers upload prescription information in the NC CSRS?

In North Carolina, the Controlled Substance Reporting System (CSRS) is designed to monitor the dispensing of controlled substances and help prevent prescription drug abuse. All options listed—oxycodone, buprenorphine, and alprazolam—are classified as controlled substances and are subject to the reporting requirements in the CSRS.

Oxycodone is an opioid pain medication, buprenorphine is used for both pain management and as part of a treatment strategy for opioid use disorder, and alprazolam is a benzodiazepine that is prescribed for anxiety and panic disorders. Because these medications can be misused and have a high potential for abuse, their dispensing must be closely monitored.

As such, dispensers must upload prescription information to the NC CSRS for all three medications. This helps ensure effective monitoring of controlled substances in the state and supports efforts to combat prescription drug abuse. Consequently, the answer includes all these medications.