Which category of drugs is commonly associated with the highest potential for abuse?

Schedule II drugs are recognized for having a high potential for abuse that may lead to severe psychological or physical dependence. This classification is established by the Controlled Substances Act, which specifically categorizes drugs based on their potential for abuse, medical use, and safety or dependence risk.

Examples of Schedule II drugs include opioids like oxycodone and morphine, and stimulants such as amphetamines. These substances are prescribed for legitimate medical reasons but pose significant risks due to their addictive nature. As a result, they are subjected to stricter regulations regarding their prescription, dispensing, and record-keeping compared to other drug categories.

In contrast, non-controlled substances, which fall outside of the controlled substances schedule, do not have a recognized potential for abuse. Schedule III drugs have a lower potential for abuse than Schedule II substances, as they are less likely to lead to severe dependence or addiction. Prescription-only medications include a broad range of drugs, some of which may be non-controlled and carry little to no abuse potential. Therefore, the designation of Schedule II accurately identifies the class of drugs most associated with high potential for abuse and necessitates careful regulation.